Wuwei heavy ion medical machine is the most compact heavy ion accelerator cancer treatment device in the world. The perimeter of the synchronous ring is as small as 56.1m, and the height difference between the high energy line climbing section of the device is about 19m, which is the height difference in the domestic accelerator. The device with the largest span spans tens of thousands of components, and many critical components require sub-millimeter installations. Wuwei heavy ion cancer treatment installations require high positioning accuracy components including beam position detectors, high-frequency cavity, electrostatic deflection plate, peeling film, etc., in which the accuracy of the synchronization ring quadrupoles requirements 0.1mm, part of the oversized, overweight components problems such as narrow installation and installation space and inadequate visibility conditions have caused many difficulties in the installation of collimation. Through the application of new techniques and methods in alignment, the technical difficulties of various alignmentinstallations are solved, and all the components of the device are installed in place with high efficiency and high precision in a short time.The collimated installation of Wuwei's heavy ion cancer treatment equipment began in April 2014 and completed the installation of the global control network, the encryption of local control networks, and the placement and scribing of various beamline components. Completed installation in September 2014, from the ion source to the cyclotron injection system, to the alignment of the medium energy transport line, the synchronous storage ring, to the high energy transport line, and the various treatment terminals. It took more than a year . Through the continuous efforts and cooperation of the staff of various systems of heavy ion cancer treatment devices, Wuwei’s heavy ion cancer treatment device successfully emerged in December 2015, enabling the Wuwei heavy ion medical machine to achieve full-line carbon ion beam acceleration and The nonlinear resonance of the synchronization loop leads slowly. The injected energy is 7 MeV/u, the flow intensity is 11euA, and the terminal energy is more than 400 MeV/u, which fully meets or exceeds the original physical design index. This also proves that the basic work of Wuwei Heavy Ion Accelerator is perfect and in place, and the alignment work has also been fully affirmed.